Обсуждение:ЛД50

Untitled

Про лсд в самой статье написано другое 90.189.165.69 20:07, 16 февраля 2011 (UTC)

ОЧЕНЬ КРИВАЯ СТАТЬЯ!

Нигде не сказано, что LD50 обязательно указывается со способом воздействия на организм (внутривенно ли, перорально ли и т.п.), так же ничего не сказано, что вообще-то надо указывать обязательно ещё и ПЕРИОД, в течение которого половина испытуемых погибает. Короче, смотрите английскую версию - там всё понятно. 77.51.139.12 21:02, 10 февраля 2014 (UTC)доброжелатель Я тупо фигачу данные из англовики, пытаюсь проверять, но если найдёте ошибки — правьте. QP • о • в 21:50, 3 марта 2014 (UTC)

про радиологию ни слова.. — Tpyvvikky (обс.) 12:37, 24 октября 2020 (UTC)

Данные не точны

Проверил 2 - аспирин и кофеин. Привожу точный источник: https://toxnet.nlm.nih.gov/cgi-bin/sis/search2

АСПИРИН

Human Toxicity Values:
Potentially lethal intoxication develops /in children/ after ingestions of 6 tablets/kg (480 mg/kg).

[Ellenhorn, M.J. and D.G. Barceloux. Medical Toxicology - Diagnosis and Treatment of Human Poisoning. New York, NY: Elsevier Science Publishing Co., Inc. 1988., p. 562] **PEER REVIEWED**
Non-Human Toxicity Values:
LD50 RABBIT ORAL 1800 MG/KG
[Sunshine, I. (ed.). CRC Handbook of Analytical Toxicology. Cleveland: The Chemical Rubber Co., 1969., p. 3] **PEER REVIEWED**
LD50 RABBIT INTRAPERITONEAL 500 MG/KG
[Sunshine, I. (ed.). CRC Handbook of Analytical Toxicology. Cleveland: The Chemical Rubber Co., 1969., p. 3] **PEER REVIEWED**
LD50 Rat oral 1500 mg/kg
[American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's with Other World Wide Occupational Exposure Values. CD-ROM Cincinnati, OH 45240-1634 2007.] **PEER REVIEWED**
LD50 Rat oral 200 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 57] **PEER REVIEWED**
LD50 Rat ip 340 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 57] **PEER REVIEWED**
LD50 Mouse oral 1100 mg/kg
[American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's with Other World Wide Occupational Exposure Values. CD-ROM Cincinnati, OH 45240-1634 2007.] **PEER REVIEWED**
LD50 Mouse oral 250 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 57] **PEER REVIEWED**
LD50 Mouse ip 280 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 57] **PEER REVIEWED**
LD50 Mouse sc 1020 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 57] **PEER REVIEWED**
LD50 Dog oral 700 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 57] **PEER REVIEWED**

— https://toxnet.nlm.nih.gov/cgi-bin/sis/search

КОФЕИН

Human Toxicity Values:
In adults, iv doses of 57 mg/kg and oral doses of 18-50 g have been fatal.
[American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2569] **PEER REVIEWED**
In one 5-year-old patient, death occurred following oral ingestion of approximately 3 g of caffeine.
[American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2569] **PEER REVIEWED**

Источник <https://toxnet.nlm.nih.gov/cgi-bin/sis/search2>

Non-Human Toxicity Values:
LD50 Rat ip 260 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Rat oral 192 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Rat rectal 300 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Rat iv 105 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Rat sc 170 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Mouse oral 127 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Mouse ip 168 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Mouse iv 62 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Mouse sc 270 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Dog oral 140 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 666] **PEER REVIEWED**
LD50 Rabbit oral 224 mg/kg
[IUCLID Data Sheets for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: http://esis.jrc.ec.europa.eu/doc/IUCLID/data_sheets/58082.pdf] **PEER REVIEWED**
LD50 Guinea pig oral 230 mg/kg
[IUCLID Data Sheets for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: http://esis.jrc.ec.europa.eu/doc/IUCLID/data_sheets/58082.pdf] **PEER REVIEWED**
LD50 Hamster oral 230 mg/kg
[IUCLID Data Sheets for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: http://esis.jrc.ec.europa.eu/doc/IUCLID/data_sheets/58082.pdf] **PEER REVIEWED**

213.184.249.123 17:22, 12 февраля 2018 (UTC)

DL50

Обыкновенное латинское выражение Dosis Letalis превратилось в старо-греко-латинский микс. --Yan.gorev (обс.) 11:39, 18 ноября 2018 (UTC)

Нигде не раскрывается значение цифры 50

Нигде не раскрывается значение цифры 50

• 50% умирают, 50% выживают. ЛД - летальная доза. MBH 22:40, 14 марта 2021 (UTC)