English: The unpiloted ISS Progress 41 supply vehicle departs from the International Space Station at 7:41 a.m. (EDT) on April 22, 2011. Filled with trash and discarded items, Progress 41 will remain in orbit a safe distance from the station for engineering tests before being commanded by flight controllers to descend to a destructive re-entry into Earth's atmosphere over the Pacific Ocean. The departure of Progress 41 clears the way for the next unpiloted supply ship, ISS Progress 42, which is set to launch April 27 from the Baikonur Cosmodrome in Kazakhstan, delivering three tons of food, fuel and supplies for the Expedition 27 crew.