English: Actin-enriched flectopodia are associated with modifications in pericyte contractility. Confocal video showing GFP-actin-U87 cells (green) interacting with pericytes plated a on a laminin-coated silicone substrate. The contact of actin-enriched extensions of a GBM cell with the substrate (white arrows) is linked to new wrinkle-formation (red arrows), indicative of altered pericyte contractility. Yellow arrows point to substrate-relaxation following the retraction of the cell extension. Cyan arrows point to a GFPactin+-cytoplasmic fragment (which varies between 3.6 and 4 µm in diameter, lines indicate the trajectory), moving onto the substrate in tight contact with pericytes. Δtime: 7 minutes; time: 2 hour 30 min; rate: 2 fps.