English: A) HPLC-UV chromatograms of YB and SR extracts with or without PVPP treatment. Asterisk marks internal standard (4-HB). B) After treatment of HUVECs with each 1% tea extract for 20 min, cells were stimulated with thrombin for 5 min and then lysed. Total proteins were analyzed by western blot. Relative band intensity (pMRLC/MRLC) is expressed as a percentage, calculated from value in tea extract-treated cells compared with that in non-treated control cells (+thrombin). Values shown are means ± SEM (n = 3). C) Total ion current chromatograms of SR with or without PVPP treatment. Asterisk marks internal standard (4-HB). D) OPLS-DA score plots and E) loading S-plots derived from each LC-MS data set (SR vs SR+PVPP). S-plot shows the covariance w against the correlation p (corr) of variables of the discriminating component of OPLS-DA model. Cut-off values for the p (corr) < |0.8| were used to select metabolites that most strongly contributed to differences between two tea extracts.