English: Adhesion of Vwf +/+ platelets. Proplatelets and large condensed platelets are present. Notice in particular the dumbbell-shaped proplatelet (arrowhead) that translocates on the surface to adopt a more condensed shape, then extends again as a multibodied proplatelet, followed by the appearance of a small discoid extension at 24′05″ (arrow) that continues to extend progressively and may correspond to a small discoid platelet (arrow) about to be released by a larger proplatelet (arrowhead) on the last frames. Note that reversibly adherent Vwf −/− proplatelets are larger than Vwf +/+ proplatelets. Bar is 20 µm.