Антагонисты 5-HT1A-рецепторов: различия между версиями
Перейти к навигации
Перейти к поиску
[отпатрулированная версия] | [отпатрулированная версия] |
Содержимое удалено Содержимое добавлено
Нет описания правки |
|||
Строка 1: | Строка 1: | ||
[[Антагонист]]ами [[5-HT1A]] подтипа [[серотониновые рецепторы|серотониновых]] [[рецептор]]ов являются многие химические вещества и [[лекарство|лекарства]], в частности, некоторые [[бета-блокатор]]ы, некоторые типичные и атипичные [[антипсихотик]]и, некоторые [[мигрень|антимигренозные]] препараты. |
[[Антагонист]]ами [[5-HT1A]] подтипа [[серотониновые рецепторы|серотониновых]] [[рецептор]]ов являются многие химические вещества и [[лекарство|лекарства]], в частности, некоторые [[бета-блокатор]]ы, некоторые типичные и атипичные [[антипсихотик]]и, некоторые [[мигрень|антимигренозные]] препараты. |
||
⚫ | |||
{{Нет ссылок в разделе|дата=21 фев 2015}} |
|||
⚫ | |||
* [[Алпренолол]]<ref>{{статья|автор=Bjorvatn B, Neckelmann D, Ursin R.|заглавие=The 5-HT1A antagonist (-)-alprenolol fails to modify sleep or zimeldine-induced sleep-waking effects in rats.|ссылка=https://www.ncbi.nlm.nih.gov/pubmed/1388278|издание=Pharmacol Biochem Behav.|год=May 1992|том=42|выпуск=42(1)|номер=1|страницы=49-56|pmid=1388278}}</ref> |
|||
* [[Алпренолол]] |
|||
* [[Цианопиндолол]]<ref>{{статья|автор=Sánchez-López A, Centurión D, Lozano-Cuenca J, Muñoz-Islas E, Cobos-Puc LE, Villalón CM.|заглавие=Role of serotonin receptors in vascular tone in the pithed rat.|ссылка=http://www.ncbi.nlm.nih.gov/pubmed/20361490|язык=Spanish|издание=Arch Cardiol Mex.|год=Dec 2009|том=79|выпуск=79 (Suppl 2)|номер=Suppl 2|pmid= 20361490}}</ref> |
|||
* [[Цианопиндолол]] |
|||
* [[Йодоцианопиндолол]]<ref name="pmid7984276">{{статья|автор=Adham N1, Tamm JA, Salon JA, Vaysse PJ, Weinshank RL, Branchek TA.|заглавие=A single point mutation increases the affinity of serotonin 5-HT1D alpha, 5-HT1D beta, 5-HT1E and 5-HT1F receptors for beta-adrenergic antagonists.|ссылка=http://www.ncbi.nlm.nih.gov/pubmed/7984276|язык=english|издание=Neuropharmacology|год=Mar-Apr 1994|том=33|выпуск=33(3-4)|номер=3-4|страницы=387-391|pmid=7984276}}</ref> |
|||
* [[Йодоцианопиндолол]] |
|||
* [[Пиндолол]] |
* [[Пиндолол]]<ref name="pmid7984276"></ref> |
||
* [[Пропранолол]] |
* [[Пропранолол]]<ref name="pmid7984276"></ref> |
||
* [[Окспренолол]]<ref>{{статья|автор=Waldmeier PC1, Williams M, Baumann PA, Bischoff S, Sills MA, Neale RF.|заглавие=Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain.|ссылка=http://www.ncbi.nlm.nih.gov/pubmed/2905765|издание=Naunyn Schmiedebergs Arch Pharmacol.|год=Jun 1988|том=337|выпуск=337(6)|номер=6|страницы=609-620|pmid=2905765}}</ref> |
|||
* [[Окспренолол]] |
|||
== Антимигренозные препараты == |
|||
* [[Метисергид]]<ref>{{статья|автор=Seletti B, Benkelfat C, Blier P, Annable L, Gilbert F, de Montigny C.|заглавие=Serotonin1A receptor activation by flesinoxan in humans. Body temperature and neuroendocrine responses.|ссылка=http://www.nature.com/npp/journal/v13/n2/full/1380279a.html|язык=english|издание=Neuropsychopharmacology|год=Oct 1995|том=13|выпуск=13(2)|номер=2|страницы=93-104|pmid=8597527}}</ref> |
|||
* [[Метисергид]] |
|||
== Атипичные антипсихотики == |
|||
* [[Рисперидон]]<ref>{{статья|автор=Newman-Tancredi A, Gavaudan S, Conte C, Chaput C, Touzard M, Verrièle L, Audinot V, Millan MJ.|заглавие=Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.|ссылка=http://www.ncbi.nlm.nih.gov/pubmed/9760039|язык=english|издание=Eur J Pharmacol.|год=21 Aug 1998|том=355|выпуск=355(2-3)|номер=2-3|страницы=245-256|pmid=9760039}}</ref> |
|||
* [[Рисперидон]] |
|||
== Типичные антипсихотики == |
|||
* [[Спиперон]] (спироперидол)<ref>{{cite web | title = PDSP K<sub>i</sub> Database | work = Psychoactive Drug Screening Program (PDSP) | author = Roth, BL; Driscol, J | url = http://pdsp.med.unc.edu/pdsp.php | publisher = University of North Carolina at Chapel Hill and the United States National Institute of Mental Health | accessdate = 4 November 2013 | date = 12 January 2011}}</ref> |
|||
* [[Спиперон]] (спироперидол) |
|||
* [[Метитепин]]<ref name="pmid4340797">{{cite journal | author = Monachon MA, Burkard WP, Jalfre M, Haefely W | title = Blockade of central 5-hydroxytryptamine receptors by methiothepin | journal = Naunyn Schmiedebergs Arch. Pharmacol. | volume = 274 | issue = 2 | pages = 192–7 | year = 1972 | pmid = 4340797 | doi = 10.1007/BF00501854 }}</ref> |
|||
* [[Метиотепин]] |
|||
=== Разные и исследовательские препараты == |
|||
* [[BMY-7,378]]<ref name="pmid7713154">{{cite journal | author = Goetz AS, King HK, Ward SD, True TA, Rimele TJ, Saussy DL | title = BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors | journal = European Journal of Pharmacology | volume = 272 | issue = 2-3 | pages = R5–6 |date=January 1995 | pmid = 7713154 | doi = 10.1016/0014-2999(94)00751-R| url = }}</ref> |
|||
* [[AV-965]] |
|||
* [[Дотаризин]]<ref>{{cite journal | last1 = Farré | first1 = M | last2 = Roset | first2 = PN | last3 = Llorente | first3 = M | last4 = Márquez | first4 = M | last5 = Albet | first5 = C | last6 = Pérez | first6 = JA | last7 = Herrero | first7 = E | last8 = Ortíz | first8 = JA | title = Clinical pharmacokinetics and tolerability of dotarizine in healthy subjects after single and multiple oral administration | journal = Methods and findings in experimental and clinical pharmacology | volume = 19 | issue = 5 | pages = 343–50 | year = 1997 | pmid = 9379783 }}</ref><ref>{{cite journal | last1 = Montiel | first1 = C | last2 = Herrero | first2 = CJ | last3 = García-Palomero | first3 = E | last4 = Renart | first4 = J | last5 = García | first5 = AG | last6 = Lomax | first6 = RB | title = Serotonergic effects of dotarizine in coronary artery and in oocytes expressing 5-HT2 receptors | journal = European Journal of Pharmacology | volume = 332 | issue = 2 | pages = 183–93 | year = 1997 | pmid = 9286620 | doi=10.1016/S0014-2999(97)01073-X}}</ref> |
|||
* [[BMY-7,378]] |
|||
* [[Флопропион]]<ref name="urlDictionary of Organic Compounds ... - Google Books">{{cite web | url = http://books.google.com/books?id=kfhQgpqxiVgC&lpg=PA1&dq=flopropione&as_brr=3&pg=PA241#v=onepage&q=flopropione&f=false | title = Dictionary of Organic Compounds ... - Google Books | format = | work = | accessdate = }}</ref> |
|||
* [[Дотаризин]] |
|||
* [[Исамолтан]]<ref name="pmid1674359">{{cite journal | author = Rényi L, Larsson LG, Berg S, Svensson BE, Thorell G, Ross SB. | title = Biochemical and behavioural effects of isamoltane, a beta-adrenoceptor antagonist with affinity for the 5-HT1B receptor of rat brain. | journal = Naunyn Schmiedebergs Arch Pharmacol. | volume = 343 | issue = 1 | pages = 1–6 | year = 1991 | pmid = 1674359 | doi=10.1007/bf00180669}}</ref><ref name="pmid2905765">{{cite journal | author = Waldmeier PC, Williams M, Baumann PA, Bischoff S, Sills MA, Neale RF. | title = Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain. | journal = Naunyn Schmiedebergs Arch Pharmacol. | volume = 337 | issue = 6 | pages = 609–620 | year = 1988 | pmid = 2905765 | doi=10.1007/bf00175785}}</ref> |
|||
* [[Флопропион]] |
|||
* [[Лекозотан]]<ref>{{cite journal|last=Schlechter|first=LE|date=June 10, 2005|title=Lecotozan (SRA-333): A selective serotonin1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and promotes procognitive effects|journal=Journal of Pharmacology and Experimental Therapeutics|url=http://jpet.aspetjournals.org/cgi/content/short/jpet.105.086363v1|pmid=15951399|doi=10.1124/jpet.105.086363|volume=314|pages=1274–89|last2=Smith|first2=DL|last3=Rosenzweig-Lipson|first3=S|last4=Sukoff|first4=SJ|last5=Dawson|first5=LA|last6=Marquis|first6=K|last7=Jones|first7=D|last8=Piesla|first8=M|last9=Andree|first9=T|last10=Nawoschik|first10=S|last11=Harder|first11=J. A.|last12=Womack|first12=M. D.|last13=Buccafusco|first13=J|last14=Terry|first14=A. V.|last15=Hoebel|first15=B|last16=Rada|first16=P|last17=Kelly|first17=M|last18=Abou-Gharbia|first18=M|last19=Barrett|first19=J. E.|last20=Childers|first20=W|issue=3|display-authors=8}}</ref> |
|||
* [[GR-46,611]] |
|||
* [[MPPF]]<ref>{{Cite journal | author1 = D. Le Bars | title = High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635 | journal = [[Nuclear Medicine and Biology]] |date=May 1998 | volume = 25 | issue = 4 | pages = 343–350 | doi = 10.1016/S0969-8051(97)00229-1 |
|||
* [[Исамолтан]] |
|||
}}</ref> |
|||
* [[Лекозотан]] |
|||
* [[NAN-190]]<ref name="pmid19190523">{{cite journal | author = Foong JP, Bornstein JC. | title = 5-HT antagonists NAN-190 and SB 269970 block alpha2-adrenoceptors in the guinea pig. | journal = Neuroreport. | volume = 20 | issue = 3 | pages = 325–330 | year = 2009 | pmid = 19190523 | doi = 10.1097/WNR.0b013e3283232caa }}</ref> |
|||
* [[MPPF]] |
|||
* [[Пиндобинд]]<ref name="Pmid">{{cite journal | pmid = 8255924 | year = 1993 | last1 = Bell | first1 = R | last2 = Hobson | first2 = H | title = Effects of pindobind 5-hydroxytryptamine1A (5-HT1A), a novel and potent 5-HT1A antagonist, on social and agonistic behaviour in male albino mice | volume = 46 | issue = 1 | pages = 67–72 | journal = Pharmacology, Biochemistry, and Behavior | doi=10.1016/0091-3057(93)90318-N}}</ref> |
|||
* [[NAN-190]] |
|||
* [[Робалзотан]]<ref name="pmid9851589">{{cite journal | doi = 10.1016/S0014-2999(98)00667-0 | author = Jerning E, Svantesson GT, Mohell N. | title = Receptor binding characteristics of [3H]NAD-299, a new selective 5-HT1A receptor antagonist. | journal = Eur J Pharmacol. | volume = 360 | issue = 2-3 | pages = 219–225 | year = 1998 | pmid = 9851589 }}</ref> |
|||
* [[Пиндобинд]] |
|||
* [[SB-649,915]]<ref name="pmid17356576">{{cite journal | author = Starr KR, Price GW, Watson JM, Atkinson PJ, Arban R, Melotto S, Dawson LA, Hagan JJ, Upton N, Duxon MS. | title = SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test. | journal = Neuropsychopharmacology. | volume = 32 | issue = 10 | pages = 2163–2172| year = 2007 | pmid = 17356576 | doi = 10.1038/sj.npp.1301341 }}</ref> |
|||
* [[Робалзотан]] |
|||
* [[Спирамид]]<ref name="pmid11124389">{{cite journal |author=Czoty PW, Howell LL |title=Behavioral effects of AMI-193, a 5-HT(2A)- and dopamine D(2)-receptor antagonist, in the squirrel monkey |journal=Pharmacology, Biochemistry, and Behavior |volume=67 |issue=2 |pages=257–64 |date=October 2000 |pmid=11124389 |doi= 10.1016/S0091-3057(00)00321-X|url=}}</ref><ref name="pmid15610924">{{cite journal |author=Luparini MR, Garrone B, Pazzagli M, Pinza M, Pepeu G |title=A cortical GABA-5HT interaction in the mechanism of action of the antidepressant trazodone |journal=Progress in Neuro-psychopharmacology & Biological Psychiatry |volume=28 |issue=7 |pages=1117–27 |date=November 2004 |pmid=15610924 |doi=10.1016/j.pnpbp.2004.05.046 |url=}}</ref><ref name="pmid17965538">{{cite journal |author=Hamada K, Yoshida M, Isayama H, Yagi Y, Kanazashi S, Kashihara Y, Takeuchi K, Yamaguchi I |title=Possible involvement of endogenous 5-HT in aggravation of cerulein-induced acute pancreatitis in mice |journal=Journal of Pharmacological Sciences |volume=105 |issue=3 |pages=240–50 |date=November 2007 |pmid=17965538 |doi= 10.1254/jphs.FP0071049|url=}}</ref> |
|||
* [[SB-649,915]] |
|||
* [[Спироксатрин]]<ref>{{статья|автор=Terrón JA, Ibarra M, Ransanz V, Hong E, Villalón CM.|заглавие=The alpha-antiadrenergic properties of spiroxatrine, a ligand of serotonergic 5-HT1A receptors|ссылка=http://www.ncbi.nlm.nih.gov/pubmed/8105762|язык=Spanish|издание=Arch Inst Cardiol Mex.|год=Jul-Aug 1993|том=63|выпуск=63(4)|номер=4|страницы=289-295|pmid=8105762}}</ref> |
|||
* [[SDZ-216,525]] |
|||
* [[UH-301]]<ref name="pmid1830099">{{cite journal | author = Björk L, Cornfield LJ, Nelson DL, Hillver SE, Andén NE, Lewander T, Hacksell U. | title = Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects. | journal = J Pharmacol Exp Ther. | volume = 258 | issue = 1 | pages = 58–65 | year = 1991 | pmid = 1830099 }}</ref> |
|||
* [[Спирамид]] |
|||
* [[WAY-100,135]]<ref name="pmid8496920">{{cite journal | author = Cliffe IA, Brightwell CI, Fletcher A, ''et al.'' | title = (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors | journal = Journal of Medicinal Chemistry | volume = 36 | issue = 10 | pages = 1509–10 |date=May 1993 | pmid = 8496920 | doi = 10.1021/jm00062a028| url = }}</ref> |
|||
* [[Спироксатрин]] |
|||
* [[WAY-100,635]]<ref>{{Cite journal | author = A. Fletcher, E. A. Forster, D. J. Bill, G. Brown, I. A. Cliffe, J. E. Hartley, D. E. Jones, A. McLenachan, K. J. Stanhope, D. J. Critchley, K. J. Childs, V. C. Middlefell, L. Lanfumey, R. Corradetti, A. M. Laporte, H. Gozlan, M. Hamon & C. T. Dourish | title = Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist | journal = [[Behavioural Brain Research]] | volume = 73 | issue = 1-2 | pages = 337–333 | year = 1996 | pmid = 8788530 | doi = 10.1016/0166-4328(96)00118-0 }}</ref> |
|||
* [[UH-301]] |
|||
* [[Ксиламидин]]<ref>{{cite journal | last1 = Fuller | first1 = RW | last2 = Kurz | first2 = KD | last3 = Mason | first3 = NR | last4 = Cohen | first4 = ML | title = Antagonism of a peripheral vascular but not an apparently central serotonergic response by xylamidine and BW 501C67 | journal = [[European Journal of Pharmacology]] | volume = 125 | issue = 1 | pages = 71–7 | year = 1986 | pmid = 3732393 | doi=10.1016/0014-2999(86)90084-1}}</ref><ref>{{cite journal | last1 = Dedeoğlu | first1 = A | last2 = Fisher | first2 = LA | title = Central and peripheral injections of the 5-HT2 agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, modify cardiovascular function through different mechanisms | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 259 | issue = 3 | pages = 1027–34 | year = 1991 | pmid = 1762059 }}</ref><ref>{{cite journal | last1 = Baker | first1 = BJ | last2 = Duggan | first2 = JP | last3 = Barber | first3 = DJ | last4 = Booth | first4 = DA | title = Effects of dl-fenfluramine and xylamidine on gastric emptying of maintenance diet in freely feeding rats | journal = European Journal of Pharmacology | volume = 150 | issue = 1–2 | pages = 137–42 | year = 1988 | pmid = 3402534 | doi=10.1016/0014-2999(88)90759-5}}</ref> |
|||
* [[WAY-100,135]] |
|||
* [[Мефвэй]]<ref>{{Cite pmid|17015907}}</ref> |
|||
* [[WAY-100,635]] |
|||
* [[Ксиламидин]] |
|||
== Примечания == |
|||
* [[Мефвэй]] |
|||
{{примечания|4}} |
|||
[[Категория:Антагонисты 5-HT1A-рецепторов|*]] |
[[Категория:Антагонисты 5-HT1A-рецепторов|*]] |
Версия от 23:43, 25 февраля 2015
Антагонистами 5-HT1A подтипа серотониновых рецепторов являются многие химические вещества и лекарства, в частности, некоторые бета-блокаторы, некоторые типичные и атипичные антипсихотики, некоторые антимигренозные препараты.
β-адреноблокаторы
Антимигренозные препараты
Атипичные антипсихотики
Типичные антипсихотики
= Разные и исследовательские препараты
- BMY-7,378[9]
- Дотаризин[10][11]
- Флопропион[12]
- Исамолтан[13][14]
- Лекозотан[15]
- MPPF[16]
- NAN-190[17]
- Пиндобинд[18]
- Робалзотан[19]
- SB-649,915[20]
- Спирамид[21][22][23]
- Спироксатрин[24]
- UH-301[25]
- WAY-100,135[26]
- WAY-100,635[27]
- Ксиламидин[28][29][30]
- Мефвэй[31]
Примечания
- ↑ Bjorvatn B, Neckelmann D, Ursin R. The 5-HT1A antagonist (-)-alprenolol fails to modify sleep or zimeldine-induced sleep-waking effects in rats. // Pharmacol Biochem Behav.. — May 1992. — Т. 42, вып. 42(1), № 1. — С. 49-56. — PMID 1388278.
- ↑ Sánchez-López A, Centurión D, Lozano-Cuenca J, Muñoz-Islas E, Cobos-Puc LE, Villalón CM. Role of serotonin receptors in vascular tone in the pithed rat. (исп.) // Arch Cardiol Mex.. — Dec 2009. — Т. 79, вып. 79 (Suppl 2), № Suppl 2. — PMID 20361490.
- ↑ 1 2 3 Adham N1, Tamm JA, Salon JA, Vaysse PJ, Weinshank RL, Branchek TA. A single point mutation increases the affinity of serotonin 5-HT1D alpha, 5-HT1D beta, 5-HT1E and 5-HT1F receptors for beta-adrenergic antagonists. (англ.) // Neuropharmacology. — Mar-Apr 1994. — Т. 33, вып. 33(3-4), № 3-4. — С. 387-391. — PMID 7984276.
- ↑ Waldmeier PC1, Williams M, Baumann PA, Bischoff S, Sills MA, Neale RF. Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain. // Naunyn Schmiedebergs Arch Pharmacol.. — Jun 1988. — Т. 337, вып. 337(6), № 6. — С. 609-620. — PMID 2905765.
- ↑ Seletti B, Benkelfat C, Blier P, Annable L, Gilbert F, de Montigny C. Serotonin1A receptor activation by flesinoxan in humans. Body temperature and neuroendocrine responses. (англ.) // Neuropsychopharmacology. — Oct 1995. — Т. 13, вып. 13(2), № 2. — С. 93-104. — PMID 8597527.
- ↑ Newman-Tancredi A, Gavaudan S, Conte C, Chaput C, Touzard M, Verrièle L, Audinot V, Millan MJ. Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35SGTPgammaS binding study.] (англ.) // Eur J Pharmacol.. — 21 Aug 1998. — Т. 355, вып. 355(2-3), № 2-3. — С. 245-256. — PMID 9760039.
- ↑ Roth, BL; Driscol, J. PDSP Ki Database . Psychoactive Drug Screening Program (PDSP). University of North Carolina at Chapel Hill and the United States National Institute of Mental Health (12 января 2011). Дата обращения: 4 ноября 2013.
- ↑ Monachon MA, Burkard WP, Jalfre M, Haefely W (1972). "Blockade of central 5-hydroxytryptamine receptors by methiothepin". Naunyn Schmiedebergs Arch. Pharmacol. 274 (2): 192—7. doi:10.1007/BF00501854. PMID 4340797.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Goetz AS, King HK, Ward SD, True TA, Rimele TJ, Saussy DL (January 1995). "BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors". European Journal of Pharmacology. 272 (2–3): R5—6. doi:10.1016/0014-2999(94)00751-R. PMID 7713154.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Farré, M; Roset, PN; Llorente, M; Márquez, M; Albet, C; Pérez, JA; Herrero, E; Ortíz, JA (1997). "Clinical pharmacokinetics and tolerability of dotarizine in healthy subjects after single and multiple oral administration". Methods and findings in experimental and clinical pharmacology. 19 (5): 343—50. PMID 9379783.
- ↑ Montiel, C; Herrero, CJ; García-Palomero, E; Renart, J; García, AG; Lomax, RB (1997). "Serotonergic effects of dotarizine in coronary artery and in oocytes expressing 5-HT2 receptors". European Journal of Pharmacology. 332 (2): 183—93. doi:10.1016/S0014-2999(97)01073-X. PMID 9286620.
- ↑ Dictionary of Organic Compounds ... - Google Books .
- ↑ Rényi L, Larsson LG, Berg S, Svensson BE, Thorell G, Ross SB. (1991). "Biochemical and behavioural effects of isamoltane, a beta-adrenoceptor antagonist with affinity for the 5-HT1B receptor of rat brain". Naunyn Schmiedebergs Arch Pharmacol. 343 (1): 1—6. doi:10.1007/bf00180669. PMID 1674359.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Waldmeier PC, Williams M, Baumann PA, Bischoff S, Sills MA, Neale RF. (1988). "Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain". Naunyn Schmiedebergs Arch Pharmacol. 337 (6): 609—620. doi:10.1007/bf00175785. PMID 2905765.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Schlechter, LE; Smith, DL; Rosenzweig-Lipson, S; Sukoff, SJ; Dawson, LA; Marquis, K; Jones, D; Piesla, M; et al. (June 10, 2005). "Lecotozan (SRA-333): A selective serotonin1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and promotes procognitive effects". Journal of Pharmacology and Experimental Therapeutics. 314 (3): 1274—89. doi:10.1124/jpet.105.086363. PMID 15951399.
- ↑ D. Le Bars (May 1998). "High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635". Nuclear Medicine and Biology. 25 (4): 343—350. doi:10.1016/S0969-8051(97)00229-1.
- ↑ Foong JP, Bornstein JC. (2009). "5-HT antagonists NAN-190 and SB 269970 block alpha2-adrenoceptors in the guinea pig". Neuroreport. 20 (3): 325—330. doi:10.1097/WNR.0b013e3283232caa. PMID 19190523.
- ↑ Bell, R; Hobson, H (1993). "Effects of pindobind 5-hydroxytryptamine1A (5-HT1A), a novel and potent 5-HT1A antagonist, on social and agonistic behaviour in male albino mice". Pharmacology, Biochemistry, and Behavior. 46 (1): 67—72. doi:10.1016/0091-3057(93)90318-N. PMID 8255924.
- ↑ Jerning E, Svantesson GT, Mohell N. (1998). "Receptor binding characteristics of [3H]NAD-299, a new selective 5-HT1A receptor antagonist". Eur J Pharmacol. 360 (2–3): 219—225. doi:10.1016/S0014-2999(98)00667-0. PMID 9851589.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Starr KR, Price GW, Watson JM, Atkinson PJ, Arban R, Melotto S, Dawson LA, Hagan JJ, Upton N, Duxon MS. (2007). "SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test". Neuropsychopharmacology. 32 (10): 2163—2172. doi:10.1038/sj.npp.1301341. PMID 17356576.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Czoty PW, Howell LL (October 2000). "Behavioral effects of AMI-193, a 5-HT(2A)- and dopamine D(2)-receptor antagonist, in the squirrel monkey". Pharmacology, Biochemistry, and Behavior. 67 (2): 257—64. doi:10.1016/S0091-3057(00)00321-X. PMID 11124389.
- ↑ Luparini MR, Garrone B, Pazzagli M, Pinza M, Pepeu G (November 2004). "A cortical GABA-5HT interaction in the mechanism of action of the antidepressant trazodone". Progress in Neuro-psychopharmacology & Biological Psychiatry. 28 (7): 1117—27. doi:10.1016/j.pnpbp.2004.05.046. PMID 15610924.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Hamada K, Yoshida M, Isayama H, Yagi Y, Kanazashi S, Kashihara Y, Takeuchi K, Yamaguchi I (November 2007). "Possible involvement of endogenous 5-HT in aggravation of cerulein-induced acute pancreatitis in mice". Journal of Pharmacological Sciences. 105 (3): 240—50. doi:10.1254/jphs.FP0071049. PMID 17965538.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Terrón JA, Ibarra M, Ransanz V, Hong E, Villalón CM. The alpha-antiadrenergic properties of spiroxatrine, a ligand of serotonergic 5-HT1A receptors (исп.) // Arch Inst Cardiol Mex.. — Jul-Aug 1993. — Т. 63, вып. 63(4), № 4. — С. 289-295. — PMID 8105762.
- ↑ Björk L, Cornfield LJ, Nelson DL, Hillver SE, Andén NE, Lewander T, Hacksell U. (1991). "Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects". J Pharmacol Exp Ther. 258 (1): 58—65. PMID 1830099.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Cliffe IA, Brightwell CI, Fletcher A; et al. (May 1993). "(S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors". Journal of Medicinal Chemistry. 36 (10): 1509—10. doi:10.1021/jm00062a028. PMID 8496920.
{{cite journal}}
: Явное указание et al. в:|author=
(справка)Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ A. Fletcher, E. A. Forster, D. J. Bill, G. Brown, I. A. Cliffe, J. E. Hartley, D. E. Jones, A. McLenachan, K. J. Stanhope, D. J. Critchley, K. J. Childs, V. C. Middlefell, L. Lanfumey, R. Corradetti, A. M. Laporte, H. Gozlan, M. Hamon & C. T. Dourish (1996). "Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist". Behavioural Brain Research. 73 (1–2): 337—333. doi:10.1016/0166-4328(96)00118-0. PMID 8788530.
{{cite journal}}
: Википедия:Обслуживание CS1 (множественные имена: authors list) (ссылка) - ↑ Fuller, RW; Kurz, KD; Mason, NR; Cohen, ML (1986). "Antagonism of a peripheral vascular but not an apparently central serotonergic response by xylamidine and BW 501C67". European Journal of Pharmacology. 125 (1): 71—7. doi:10.1016/0014-2999(86)90084-1. PMID 3732393.
- ↑ Dedeoğlu, A; Fisher, LA (1991). "Central and peripheral injections of the 5-HT2 agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, modify cardiovascular function through different mechanisms". The Journal of Pharmacology and Experimental Therapeutics. 259 (3): 1027—34. PMID 1762059.
- ↑ Baker, BJ; Duggan, JP; Barber, DJ; Booth, DA (1988). "Effects of dl-fenfluramine and xylamidine on gastric emptying of maintenance diet in freely feeding rats". European Journal of Pharmacology. 150 (1—2): 137—42. doi:10.1016/0014-2999(88)90759-5. PMID 3402534.
- ↑ Saigal N., Pichika R., Easwaramoorthy B., Collins D., Christian B. T., Shi B., Narayanan T. K., Potkin S. G., Mukherjee J. Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate. (англ.) // Journal of nuclear medicine : official publication, Society of Nuclear Medicine. — 2006. — Vol. 47, no. 10. — P. 1697—1706. — PMID 17015907.